Cancer Education at Banner MD Anderson Cancer Center  

Glossary of Cancer Terms - Y


yangona An herb native to islands in the South Pacific. Substances taken from the root have been used in some cultures to relieve stress, anxiety, tension, sleeplessness and problems of menopause. Yangona may increase the effect of alcohol and of certain drugs used to treat anxiety and depression. The U.S. Food and Drug Administration advises users that yangona may cause severe liver damage. The scientific name is Piper methysticum. Also called kava kava, intoxicating pepper, rauschpfeffer and tonga.

yin and yang In Chinese philosophy, yin and yang are opposite forces that form a whole. Everything contains both yin and yang in a balance that is always changing, such as hot and cold, day and night, and health and disease. In traditional Chinese medicine, disease is diagnosed and treated based on the balance of yin and yang.

yohimbe (Pausinystalia yohimbe) A tree native to West Africa. The bark is used as a supplement for bodybuilding and to enhance male sexual performance. It contains the chemical yohimbine, which is being studied in the treatment of sexual dysfunction. Yohimbe may interact with certain drugs used to treat depression, high blood pressure, and high blood sugar. Also called johimbe.

yttrium A rare elemental metal. A radioactive form of yttrium is used in radiation therapy and some types of immunotherapy.

yttrium Y 90 DOTA monoclonal antibody HuPAM4 A monoclonal antibody linked to a radioactive substance. It is being studied in the treatment of advanced pancreatic cancer. The monoclonal antibody called HuPAM4 is made in the laboratory and can locate and bind to pancreatic cancer cells. It is linked to a radioactive form of yttrium that can kill cancer cells without harming normal cells. Yttrium Y 90 DOTA monoclonal antibody HuPAM4 is a type of radioimmunoconjugate.

yttrium Y 90 DOTA-biotin A compound that contains the radioisotope yttrium Y 90 linked to the chemical biotin. Biotin is a molecule that binds strongly to the chemical streptavidin. Yttrium Y 90 DOTA-biotin will find tumor cells in the body that have been targeted by an antibody linked to streptavidin and kill them. It is being studied together with CC49-streptavidin in the treatment of cancer.

yttrium Y90 ibritumomab tiuxetan An anticancer drug that is a combination of a monoclonal antibody and a radioisotope (yttrium-90). Monoclonal antibodies are made in the laboratory and can locate and bind to cancer cells. Also called IDEC-Y2B8.

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