Update December 30th, 2021: There is limited supply of currently available COVID monoclonal antibodies. Healthcare providers should evaluate patients’ medical history to determine if they are eligible for COVID monoclonal antibody. However, based on very limited supplies, not all eligible patients may receive treatment.
Banner Health is offering monoclonal antibody infusions in our outpatient infusion centers for patients who are eligible for treatment. View our COVID-19 Monoclonal Antibody Infusion Order. These antibody treatments have not been approved, but have been authorized for emergency use by the FDA, to treat mild to moderate COVID-19 in adults and pediatric patients (12 years of age or older, weighing at least 40 kg) with positive results of SARS-CoV-2 viral testing, and who are at high risk for progressing to severe COVID-19 and/or hospitalization. This authorization is only for the duration of the declaration that circumstances exist justifying the authorization of the emergency use of these antibodies under Section 564(b)(1) of the Act, 21 U.S.C. § 360bbb-3(b)(1), unless the authorization is terminated or revoked sooner.
You can refer a patient by following these steps, which includes completing the COVID-19 Monoclonal Antibody Infusion Order and faxing to an outpatient infusion center currently offering this treatment, along with the documents listed below, which must be completed and signed by a physician, physician assistant or nurse practitioner.
- Clinical note
- COVID lab result
- Patient demographic information
Patient Referral Process for Monoclonal Antibody Treatment
Information regarding the FDA’s Emergency Use Authorization for approved COVID monoclonal antibodies can be found on the FDA’s website.
Note: As of December 28th, 2021, Banner Health is pausing the administration of casirivimab/imdevimab and bamlanivimab/etesivimab based on the prevalence of omicron variant. Sotrovimab will be administered based on Banner Health’s COVID monoclonal antibody guidance and sotrovimab availability.
To refer an eligible patient for monoclonal antibody treatment, you must have:
- Patient has documentation of a positive PCR or direct antigen COVID test, or complete the COVID test questions within the referral order set.
- Confirm that your patient is at least 12 years old and have mild to moderate COVID-19 symptoms that began less than 10 days ago.
- Confirm that your patient is at high risk for developing severe symptoms or requiring hospitalization.
- Evaluate and identify what high-risk criteria is present with the patient, options include:
- Adult risk factors (age 18 or greater)
- Age 65 or greater
- Chronic kidney disease
- Immunosuppressive disease, or you’re receiving immunosuppressive treatment
- Cardiovascular disease
- Chronic lung disease such as COPD or cystic fibrosis
- Sickle cell disease
- Neurodevelopmental disorders or other medically complex conditions such as genetic conditions or metabolic syndrome
- Medical-related technology dependence such as a feeding tube
- Other medical conditions or factors, such as race or ethnicity, can also put you at high risk for developing severe COVID-19 infection.
- Pediatric Risk Factors (age 12 or greater)
- Major immune suppression (for example, recently diagnosed hematologic malignancy, cancer chemotherapy, solid organ transplant, or immune suppression)
- Medical related technology dependence (for example, tracheostomy, positive pressure ventilation)
- Obesity (> 85th percentile for age and gender)
- Patients who are not eligible to receive monoclonal antibody treatment treatment are:
- Asymptomatic patients
- If your patient has been hospitalized for COVID
- Has any other systemic infection
- Has received oxygen therapy due to COVID or requires additional oxygen if on chronic oxygen therapy.
- Review the EUA patient fact sheet, including risks and benefits with the patient who will receive the monoclonal antibody treatment. Information can be found using the links below.
- Complete a Clinical Note that indicates which high-risk factors the patient has, as well as documentation that you reviewed risks and benefits with the patient.
- Complete the COVID-19 Monoclonal Antibody Infusion Order and fax, along with the following documentation, to the preferred Banner Health outpatient infusion site.