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Can Your Medications Cause Erectile Dysfunction?

Erectile dysfunction (ED) is a condition where you can’t get or maintain an erection. It can be frustrating and confusing. But it’s common and it can happen for a lot of different reasons. 

If you have ED, it could be tied to your physical health, stress levels or aging. And it’s also possible that the medications you take may play a role. 

If you’ve noticed changes in your sexual function after starting a new medication, don’t just stop taking your medication without talking to your health care provider. You can address ED without ending important treatments. 

Bryan Herzog, MD, a urologist with Banner Health, explained more about the connection between ED and certain medications and the options you have to restore your sexual function.

How medications can affect erections 

Several body systems must work together for you to have an erection: 

  • You need enough blood flow to the penis 
  • The brain has to send nerve signals to the body 
  • Your hormone levels need to be in check

Some medications can affect these systems by: 

  • Reducing your blood flow 
  • Changing your brain chemistry 
  • Affecting your hormone levels 

Not everyone experiences side effects and they can be different from person to person. 

Common medications linked to erectile dysfunction 

“Multiple medication classes can cause erectile dysfunction (ED),” Dr. Herzog said. It’s important to know that these medications don’t cause these side effects in everyone who takes them. 

Medications with possible ED side effects fall into certain categories.

Blood pressure medications 

  • Beta blockers 
  • Certain diuretics 

Antidepressants and mental health medications 

  • SSRIs 
  • SNRIs 
  • Some anti-anxiety medications
  • Tricyclic antidepressants
  • Antipsychotics 

Hormone therapies 

Treatments that lower testosterone levels or block testosterone, including:

  • Finasteride, which is often prescribed to shrink enlarged prostates
  • GnRH agonists
  • 5 alpha-reductase inhibitors
  • Spironolactone 

Narcotics

Using narcotics long-term can lower your testosterone level, which may result in ED.

Statins

“Statins have been associated with ED but the evidence is controversial,” Dr. Herzog said. Statins may lower testosterone but they also support your overall heart health, so they could help with ED in the long run. 

Other common erectile dysfunction causes

If you’re taking a medication for an underlying condition that could cause erectile dysfunction, that condition is more likely to cause the ED than the medication itself. It’s also common for more than one factor to contribute to erectile dysfunction.

Circulation issues

Psychological causes

Neurological problems

  • Stroke
  • Multiple sclerosis
  • Spinal cord injury

Endocrine issues

  • Diabetes
  • Hypogonadism
  • Pituitary gland disorders

Lifestyle factors

  • Sleep problems 
  • Tobacco use
  • Alcohol misuse
  • Obesity
  • Sedentary lifestyle
  • Recreational drugs

What to do if you think a medication may be causing ED

Your provider can help find a solution that works for you. Don’t stop taking your medication. Ask your health care provider about:

  • Adjusting the dose of your medication
  • Trying a different medication
  • Treatment options for ED

When should you see a doctor? 

It’s important to talk to your health care provider if you have ED, since many of the issues that might be responsible for it could also be causing other health problems. 

Erectile dysfunction can be a sign of occult cardiovascular disease, which is heart disease that doesn’t cause noticeable symptoms. People who have erectile dysfunction without other known medical issues often have underlying cardiovascular disease.  

You should also talk to your provider if:

  • ED is ongoing or getting worse 
  • Symptoms start after you change a medication 
  • ED affects your quality of life or relationships 
  • You have other symptoms like fatigue or low mood 

To treat ED, your provider may:

  • Recommend healthy lifestyle choices. A heart-healthy diet also supports the blood vessels in the penis. Exercise helps with blood flow and testosterone levels.
  • Prescribe medications called PDE5-inhibitors and make sure they do not interact with your current medications.
  • Refer you to a urologist for other options that can help manage erectile dysfunction.

You may feel embarrassed or uncomfortable bringing up ED with your provider. You may want to ask questions like:

  • Is there another medication that has a lower risk of sexual side effects?
  • Could I try a lower dose to manage my condition while reducing the risk of side effects?
  • Does the time when I take my medication make a difference with sexual side effects?

Your provider understands that sexual health is an important part of your overall well-being and can work with you to find a solution.

The bottom line 

Some medications may contribute to erectile dysfunction. That doesn’t mean you have to choose between your treatment and your quality of life. With the right support, you can find options that address both needs. 

If you’re experiencing erectile dysfunction and think your medication may be a factor, a Banner Health provider can help you review your options and find a solution that works for you.

FAQs

Can medications cause erectile dysfunction? 

Yes, some medications can affect blood flow, hormones or nerve signals involved in erections. 

Which medications are most likely to cause ED? 

Blood pressure medications, antidepressants and some hormone therapies are commonly linked. 

Should I stop taking my medication if I have ED? 

No. Always talk to your provider before making changes. 

Can ED caused by my medication be reversed? 

Adjusting medication or adding treatment may help. 

Is ED always caused by medication? 

No. It’s often related to multiple factors, including health conditions and stress. 

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