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Patent Foramen Ovale (PFO): What Adults Need to Know

You might be surprised to learn you were born with a heart condition as an adult. Some people find out they have a patent foramen ovale (PFO) after testing for migraines, a stroke or other health issues. A PFO is common and usually doesn’t cause symptoms, so it can go unnoticed for years.

At Banner Health, our heart specialists use advanced imaging and minimally invasive treatments to create a care plan just for you. Learning you have a heart condition can feel unexpected but you don’t have to navigate it alone.   

What is a patent foramen ovale (PFO)?

A patent foramen ovale is a small flap-like opening between the two upper chambers of the heart. Everyone has this opening before birth. It helps blood flow through the heart as a baby grows in the womb (uterus). Usually, it closes before a child turns 3.

“Patent” means open, and “foramen ovale” is the small flap. When it stays open after age 3, it is called a patent foramen ovale.

A PFO is considered a congenital heart condition because people are born with it. But unlike many heart defects you are born with, a PFO is often mild and may not be discovered until adulthood.

How common is PFO?

PFO is common. About one in four adults have it. Most people don’t know they have it until later in life. Some find out during a routine test, while others discover it after a health problem sends them to a health care specialist.

What does the foramen ovale do?

Before a baby is born, it doesn't use its lungs to breathe. Instead, oxygen goes through the placenta. Because of this, blood flows differently through the baby's heart while developing.

The foramen ovale is an opening between the right and left upper chambers of the heart. This opening allows blood to skip the lungs before birth. After birth, the lungs start working and changes in pressure usually close this opening.

If the foramen ovale does not close after birth, it is called a PFO. It can go unnoticed for many years, but it is a type of heart condition that people are born with.

What causes a PFO?

A patent foramen ovale is not caused by anything you did or didn’t do. It doesn’t come from your diet, habits or how much you exercise.

Experts don’t fully understand why the opening stays partly open in some people. But genetics might play a small role.

PFO is common and can happen in healthy people. Most adults with a PFO go for years without any symptoms or problems.

Symptoms of patent foramen ovale

Most people with a PFO show no symptoms. When symptoms appear, they usually come from another condition linked to the foramen ovale, not the opening itself. 

Some people learn they have a PFO after:

  • A stroke or transient ischemic attack (TIA or mini-stroke)
  • Ongoing migraine headaches
  • Shortness of breath in certain positions
  • Low oxygen levels without another clear cause

How is PFO linked to stroke?

Normally, the heart pumps blood into the lungs. The lungs filter out small clots before the blood leaves. When you have a PFO, some blood can bypass this filter by slipping through the open flap. If a clot passes through, it can travel to the brain and block a blood vessel. This is called a PFO-associated stroke. 

Not everyone with a PFO will have a stroke. The risk remains low for most people. But if you have had one tied to a PFO, your care team will help you lower the chance of another incident.

Learn about different stroke types

How is a patent foramen ovale diagnosed?

Because a PFO often doesn’t cause symptoms, health care providers usually find it while testing for other problems. They might suggest tests if you've had an unexplained stroke, migraines or other symptoms that could be linked to a PFO.

Tests may include:

  • Echocardiogram: This test uses sound waves to make pictures of your heart. It shows how blood flows through your heart.
  • Bubble study: During this test, saline mixed with tiny bubbles is injected into a vein. If the bubbles move between the upper chambers of the heart, it might mean you have a PFO.
  • Transesophageal echocardiogram (TEE): This test uses a thin tube placed into your esophagus to get detailed images of your heart.
  • Heart rhythm monitoring: Some people wear a monitor to check for unusual heart rhythms that could increase the risk of stroke.

When does a PFO need treatment?

Not everyone with a PFO needs treatment. Your provider might just watch the condition if you have no symptoms or other health problems. 

Treatment may be recommended if:

  • You had a stroke with no other clear cause
  • You have repeated mini-strokes
  • You have low oxygen levels related to the PFO
  • You are a scuba diver with decompression sickness linked to PFO

Your care team will discuss the benefits and risks of treatment with you, based on your personal health history and goals. 

What are the treatment options for a PFO?

Treatment depends on your symptoms, age and risk factors. It might include:

Medications

Some people take medications to help lower the risk of blood clots. This might be enough for those who do not need a medical procedure. These medicines may include:

  • Aspirin or other antiplatelet medicines
  • Blood thinners in some cases

PFO closure procedure

Some adults can get help by closing the opening. A PFO closure is usually a minimally invasive procedure. A cardiologist guides a thin tube called a catheter through a blood vessel (often in the groin) to the heart. They place a small device to seal the opening. Over time, heart tissue grows around the device.

Most people go home the same day or the next day. The recovery is faster than open-heart surgery because the chest doesn’t need to be opened.

After the procedure, you might feel mild soreness or bruising where the catheter was inserted. Your care team will give you instructions on activity limits and medications to help you heal. Your doctor may ask you to avoid heavy lifting or intense exercise for a short time.

Heart surgery

If a PFO closure isn’t possible, your doctor might suggest minimally invasive heart surgery or open-heart surgery

Living with a PFO

Most people with a patent foramen ovale live full, active lives. They continue working, exercising, traveling and spending time with family just like before.

Some people never need treatment. Others feel more at ease after learning the cause of their symptoms or completing treatment.

A few helpful steps can support your long-term health:

  • Keep up with appointments with your provider
  • Take any prescribed medication on time
  • Tell your dentist and other doctors about your PFO
  • Keep moving your body, eating well and getting enough rest

If you plan to scuba dive or take a long flight soon, ask your provider for guidance. In rare cases, a PFO can increase the risk of decompression sickness or blood clots from sitting too long.

When should you talk to a doctor?

Talk with your health care provider if you:

  • Had a stroke or mini-stroke without a clear cause
  • Have frequent migraines with aura 
  • Experience unexplained shortness of breath or low oxygen levels
  • Have questions after learning you have a PFO

Why choose Banner Health for a PFO?

At Banner Health, we are experts in diagnosing and treating patent foramen ovale and other heart conditions. Here’s why patients choose us:

  • Expertise in structural heart procedures
  • Minimally invasive treatment options
  • Team-based care, including cardiology and neurology
  • Personalized treatment plans
  • Advanced imaging and diagnostics 

If you have been told you have a PFO or had a stroke without a clear cause, our team can help you understand your choices. Book an appointment today.

Frequently asked questions about PFO

Is a PFO dangerous?

No. Usually, a PFO is not dangerous and causes no symptoms. But in rare cases, it can allow blood clots to bypass the lungs and travel to the brain, increasing the risk of stroke.

Can a PFO close on its own?

No. Once you reach adulthood, the flap will not close on its own. The good news is that most PFOs do not require closure. 

Do I need surgery for a PFO?

Most people with a patent foramen ovale never need surgery. A PFO needs closure only if you have had an unexplained stroke, a TIA or other complications. 

Can a PFO cause migraines?

A PFO is strongly associated with migraine with aura, migraine aura without headache and chronic migraine. 

What’s the difference between a PFO and an atrial septal defect?

A PFO is a small flap-like opening in the heart that doesn’t fully close after birth. An atrial septal defect (ASD) is a true hole in the wall between the upper chambers of the heart. ASDs are usually bigger and can affect blood flow. Some ASDs need treatment early in life but many do not. PFOs usually don’t cause any symptoms. 

Can exercise affect a PFO?

Most people with a PFO can exercise safely. Ask your provider if you have a history of stroke, low oxygen levels or other heart concerns. 

Can children have a PFO?

A PFO begins before birth. Most babies' openings close naturally after they are born. Some people have a PFO into adulthood without realizing it.