✖
Banner Health
Making healthcare easier
INSTALL

Complex Regional Pain Syndrome

Recovering from an injury or surgery takes time. But if your pain seems much worse than expected or it isn’t getting better, you might have complex regional pain syndrome (CRPS).

CRPS is a chronic pain condition that can develop after an injury, surgery or medical event. The original injury may have healed but the nervous system keeps sending pain signals that are stronger and last longer than they should.

At Banner Health, our pain management, neurology and rehabilitation experts work together to check your symptoms, confirm a diagnosis and create a personalized treatment plan. Our goal is to reduce pain, improve movement and help you get back to the activities you enjoy.

What is complex regional pain syndrome?

CRPS is a rare condition that causes pain, skin color changes and other symptoms in certain parts of your body. It often occurs after an injury, surgery or trauma and the pain is usually much worse than expected. Without treatment, it can last for months or even years.

CRPS most often affects one limb, like a hand, wrist, arm, foot, ankle or leg. For some people, symptoms stay in one spot. For others, they spread to nearby areas including the face.

Types of complex regional pain syndrome

There are two types of CRPS:

  • Type 1 (reflex sympathetic dystrophy): Happens without a clear nerve injury
  • Type 2 (causalgia): Happens when there is a confirmed nerve injury

Both types cause similar symptoms and are treated in the same way. Some people are first diagnosed with Type 1 but later tests reveal nerve damage and the diagnosis changes to Type 2.

What causes CRPS?

Researchers are still studying what causes CRPS. It seems to involve changes in the nervous system, immune system and blood flow that keep pain signals active even after the body starts healing.

It can develop after:

  • A broken bone
  • Sprain or strain
  • Surgery
  • Cut or burn
  • Crush injury
  • Sports injury
  • Car accident
  • Nerve injury
  • Heart attack or stroke

Sometimes, CRPS follows a very minor injury. Other times, there is no clear cause. Having an injury doesn’t mean you’ll develop CRPS.

Who is most at risk for CRPS?

CRPS can affect anyone but your risk may be higher if you:

  • Recently had an injury or surgery
  • Have a fracture or nerve injury
  • Are between 40 and 70
  • Are female
  • Had prolonged immobilization, such as with a cast
  • Have inflammatory or chronic pain conditions like migraines

Most people who have an injury or surgery never develop CRPS. It’s rare and doctors can’t always predict who will get it.

Symptoms of complex regional pain syndrome

CRPS usually appears within days or weeks after an injury or surgery, though it can develop later. The main symptom is chronic pain that’s often much worse than the original injury. It may feel like burning, shooting, stabbing or like “pins and needles.”

Other symptoms include

  • Allodynia: Light touches, clothing or a gentle breeze may cause severe pain.
  • Swelling: The affected arm or leg might become swollen.
  • Skin color changes: The skin may turn red, purple, blue, pale or blotchy.
  • Temperature changes: The affected limb may feel warmer or colder than the other side.
  • Sweating changes: You may notice more sweating or differences in sweating between limbs.
  • Changes in hair, skin and nails: Over time, hair growth might speed up or slow down; nails can become brittle or grow faster; and the skin may appear thin, shiny or dry.
  • Stiffness and limited movement: Pain and swelling can cause joints to become stiff and muscles tight, making movement and walking more difficult.
  • Muscle weakness: Pain can cause muscles to weaken over time and some people may also experience muscle spasms or tremors.

How is CRPS diagnosed?

There is no single test for CRPS. Your health care provider will review your symptoms and medical history and perform a physical exam. They may also use the Budapest Criteria, a common set of guidelines that help diagnose CRPS based on exam findings.

Tests to rule out other conditions

Your provider may order tests to rule out other causes of your symptoms, including:

  • X-rays to look for bone changes or fractures
  • MRI to evaluate bones, joints and soft tissues
  • Bone scan to look for changes in bone metabolism that may occur with CRPS
  • Nerve conduction studies or electromyography (EMG) if a nerve injury is suspected
  • Blood tests to check for infection, inflammation or other medical conditions

How is CRPS treated?

The earlier CRPS is treated, the better your chances of improving pain and function. Because CRPS affects everyone differently, your treatment will be tailored to your symptoms, health and daily life. The main goals are to reduce pain, improve movement and help you use the affected limb as much as possible.

Physical and occupational therapy

Physical and occupational therapy play a key role in CRPS treatment. Gentle, guided movement can improve flexibility, strength and range of motion, reduce stiffness and build your confidence in using the affected limb.

A physical therapist can guide you through:

  • Stretching exercises
  • Strengthening, balance and coordination exercises
  • Desensitization techniques to lessen touch pain
  • Mirror therapy and graded motor imagery to help retrain how your brain responds to pain

An occupational therapist can teach you new ways to do daily tasks while protecting the limb and improving how it functions.

Medicines and treatments

Several types of medicine can help calm the overactive pain signals in the brain and spinal cord.

Your doctor might recommend:

  • Nerve medicines like gabapentin or pregabalin
  • Certain antidepressants that ease nerve pain
  • Over-the-counter (OTC) NSAIDs
  • Corticosteroids to reduce swelling
  • Topical creams or patches with numbing medicine
  • Nerve blocks or sympathetic nerve blocks

Learn about treating neuropathic nerve pain.

Advanced treatments

Advanced treatments like neuromodulation may help with pain signals. Some of these advanced treatments include spinal cord stimulation and dorsal root ganglion (DRG) stimulation.

  • Spinal cord stimulation uses a small, implanted device that sends gentle electrical signals to the spinal cord, blocking pain messages before they reach your brain.
  • DRG stimulation targets specific nerves that cause pain in one area, such as the foot, ankle, knee or groin.

You’ll usually try a temporary device first to see if it helps before getting a permanent one. Your care team can help you decide if these treatments are right for you.

Behavioral health

Living with chronic pain affects more than just your body. It can also impact your sleep, mood, relationships and emotional health. Behavioral health specialists can help you learn healthy ways to cope, manage stress and anxiety and improve your overall well-being.

Other treatments

Depending on your symptoms, your provider may also recommend:

  • Transcutaneous electrical nerve stimulation (TENS)
  • Heat or cold therapy, if tolerated
  • Compression garments for swelling
  • Home exercise programs
  • Lifestyle changes that support healthy circulation and movement

Your pain management specialist will work with you to build a treatment plan that fits your needs and goals.

Living with CRPS

Living with chronic pain can be challenging. CRPS may affect your ability to work, exercise, sleep or enjoy everyday activities. It can also be frustrating when your pain does not match what others can see.

A treatment plan that focuses on both pain relief and improving function can help you move forward.

Helpful strategies may include:

  • Staying active within limits: Your care team can help you find safe ways to stay active.
  • Tracking your symptoms: Keep a record of your pain levels, triggers and symptoms to help you and your care team see what’s working.
  • Taking care of your overall health: Get enough sleep, eat a balanced diet, stay active within your limits and manage stress.
  • Building a support system: Chronic pain can feel isolating. Support from family, friends, support groups and mental health professionals can help you manage emotional challenges.

When to see a specialist

Talk with your provider if you have severe or ongoing pain after an injury or surgery, especially in an arm, leg, hand or foot.

You may benefit from seeing a pain management or neurology specialist if you have:

  • Symptoms that aren't improving with usual injury care
  • Pain that’s worse than expected
  • Burning or stabbing pain
  • Swelling
  • Skin or temperature changes
  • Extreme sensitivity to touch
  • Stiffness or weakness
  • Pain that affects your sleep, mood or daily activities

When should I seek emergency care?

Call 911 or go to the nearest emergency room if you have:

  • Sudden, severe swelling
  • Fever or spreading redness
  • Chest pain or trouble breathing
  • Sudden weakness or loss of feeling
  • A cold, pale or blue limb
  • Symptoms of a blood clot

Why choose Banner Health for CRPS care?

Living with complex regional pain syndrome can be frustrating but you don't have to manage it alone. Banner Health offers comprehensive CRPS care through our pain management, neurology and rehabilitation teams. We work together to identify the cause of your symptoms, rule out other conditions and help reduce your pain and improve movement.

When you choose Banner Health, you'll find:

  • Evaluation for severe pain after an injury or surgery
  • Access to pain management and neurology specialists
  • Personalized treatment for chronic nerve pain
  • Coordination with physical and occupational therapy
  • Support for pain that affects sleep, movement, mood and daily life
  • Ongoing care as your needs change

Whether your symptoms are new or you’ve lived with CRPS for years, our team is here to help you explore your treatment options and improve your quality of life.

Make an appointment today.

FAQs

What is complex regional pain syndrome?

CRPS is a chronic pain condition that often affects an arm, leg, hand or foot after an injury or surgery. The pain is usually worse or lasts longer than expected.

What does CRPS feel like?

CRPS may feel like burning, stabbing, throbbing or severe sensitivity to touch, sometimes with swelling, skin or temperature changes, stiffness or weakness.

What causes CRPS?

CRPS often starts after an injury, fracture, sprain, surgery or nerve injury. In some cases, there is no clear cause.

Is CRPS nerve pain?

CRPS involves the nervous system, inflammation and changes in blood flow, so many people have nerve-type pain, such as burning, shooting or sensitivity to touch.

How is CRPS diagnosed?

There is no single test for CRPS. Diagnosis is usually based on symptoms, medical history and a physical exam. Tests may be used to rule out other causes.

Can CRPS be treated?

Yes. Treatment may help reduce pain and improve movement. Care may include physical or occupational therapy, medicines, pain management procedures and behavioral health support.

Can CRPS go away?

Some people improve over time, especially with early treatment. Others have long-term symptoms that need ongoing pain management and rehabilitation.

When should I see a doctor for possible CRPS?

See a provider if pain after an injury or surgery is severe, lasts longer than expected or comes with swelling, skin color changes, temperature changes or extreme sensitivity to touch.