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Thyroid Cancer Treatment and Support

Thyroid cancer is one of the most treatable types of cancer, especially when found early. Even if it spreads beyond the thyroid, many people do very well with treatment and can live active, full lives. 

At Banner MD Anderson Cancer Center, our team guides you through every step of your care. Our thyroid specialists use some of the latest science, advanced surgical techniques and supportive services to help you heal and stay informed.   

How thyroid cancer is treated

Many people with thyroid cancer need more than one type of treatment. Your care team might recommend surgery, radioactive iodine therapy, hormone therapy, targeted or systemic treatments or a combination of these options. 

The type of treatment depends on the type of thyroid cancer:

  • Papillary and follicular thyroid cancers: Usually treated with surgery and radioactive iodine
  • Medullary thyroid cancer: May require surgery and sometimes targeted therapy
  • Anaplastic thyroid cancer: Rare and fast-growing, often treated with systematic treatment using targeted therapy, surgery and sometimes radiation 

Other factors also guide treatment, such as cancer stage, if it has spread to lymph nodes or other organs, your age and overall health and findings from imaging, biopsy and molecular testing.

Thyroid surgery

Surgery is often the first treatment for many thyroid cancers. The goal is to remove the cancer while protecting nearby nerves and structures. 

Types of surgery include: 

  • Lobectomy: Removes the half of the thyroid that has cancer. Often used for small, low-risk cancers.
  • Total thyroidectomy: Removes the entire thyroid. Used for larger cancers, those affecting both sides or those involving lymph nodes.
  • Lymph node dissection: Removes affected lymph nodes to reduce the risk of recurrence. 

Because Banner MD Anderson surgeons specialize in complex thyroid and neck surgeries, you can feel confident you’re receiving precise, quality care. 

Radioactive iodine (RAI) therapy

After surgery, some patients benefit from radioactive iodine therapy. This treatment helps destroy any remaining thyroid tissue or cancer cells. 

RAI is most often used for:

  • Papillary thyroid cancer
  • Follicular thyroid cancer

How it works:

  • You swallow a capsule or liquid containing radioactive iodine.
  • The iodine travels to thyroid cells and destroys them. 
  • Most people go home the same day with temporary safety precautions.

Side effects are usually mild, such as dry mouth, fatigue or taste changes. 

Your care team will let you know whether RAI is recommended based on your pathology, staging and risk factors. 

Thyroid hormone replacement therapy

After thyroid surgery, especially total thyroidectomy, you’ll need lifelong thyroid hormone replacement. This medicine is called levothyroxine, a small pill you will take every day.

Levothyroxine:

  • Keeps your metabolism balanced
  • Supports your overall health
  • Helps lower the chance of cancer returning

Because levothyroxine must be very precisely titrated (measured), your endocrinologist will monitor your hormone levels and adjust your dose as needed to achieve optimal health.

External beam radiation therapy

Radiation therapy uses high-energy beams to destroy cancer cells. It is not commonly used for most thyroid cancers but may help for:

  • Medullary thyroid cancer
  • Anaplastic thyroid cancer
  • Recurrent neck cancers
  • Cases where RAI is not effective

What to expect:

  • Treatments are usually given five days a week for several weeks
  • Each session is quick and painless
  • Side effects may include skin redness, fatigue or trouble swallowing 

Our radiation oncologists use highly targeted approaches to protect healthy tissue while delivering powerful treatment to the cancer. 

Targeted therapy and systemic treatments

For cancers that have spread or resist standard treatments, Banner MD Anderson offers advanced therapies, including:

  • Targeted therapies for specific changes (mutations) in cancer cells
  • Immunotherapy to help your own immune system destroy the cancer
  • Systemic treatments that target cancer cells throughout the body 

Targeted therapy works by blocking specific genes or proteins that cancer cells use to grow. Therapies might include:

  • Tyrosine Kinase inhibitors: Help block cancer cell growth and may shrink tumors
  • RET-targeted drugs: Useful for medullary thyroid cancer with RET gene changes
  • BRAF or MEK inhibitors: Used for cancers with BRAF mutations

Systemic treatments are medicines that move through your bloodstream to find and destroy cancer cells anywhere in your body. They don’t only target the thyroid area. 

Systemic treatments might include:

Molecular testing performed during diagnosis helps determine which therapies may work best for you.

Clinical trials

At Banner MD Anderson, you may have access to clinical trials offering new or emerging therapies. Trials are especially valuable for:

  • Advanced papillary or follicular cancer
  • Oncocytic carcinoma
  • Medullary thyroid cancer
  • Anaplastic thyroid cancer

Your care team will explain options clearly so you can decide what’s right for you. 

Managing side effects

Your health is more than test results and treatments. It’s also about how you feel every day. Your care team will help you manage:

  • Fatigue
  • Hoarse voice
  • Low calcium levels after surgery
  • Changes in appetite or weight
  • Dry mouth from RAI
  • Mood changes from hormone shifts

Tell your care team about any symptoms you have. There are many ways to help you feel better during treatment and recovery. 

Emotional and practical support

A thyroid cancer diagnosis can bring many emotions. Banner MD Anderson offers thyroid cancer support services such as:

You will not face this alone. Our team helps you manage symptoms, understand medications and plan for life after cancer. 

What follow-up care looks like

Thyroid cancer often requires long-term monitoring. Your follow-up plan may include:

  • Regular physical exams
  • Thyroid hormone checks
  • Ultrasounds
  • Blood tests such as thyroglobulin
  • Imaging tests like CT, MRI or PET scans (based on your cancer type and stage)

How often you need follow-up appointments depends on what kind of cancer you had and if it was high or low risk. 

Is thyroid cancer curable?

Most thyroid cancers are highly treatable and have excellent long-term outcomes. Early detection and personalized care further improve outcomes. Your care team will explain what to expect and guide you through your entire journey.

Learn more about thyroid cancer

Your next step: Find a thyroid cancer specialist

Choosing where to get cancer treatment is one of the most important decisions you will make. At Banner MD Anderson, our team provides expert, compassionate care for every step of your thyroid cancer journey.  

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